Application of High Performance Liquid Chromatography for the Measurements of Lipophilicity and Biomimetic Binding Properties in Drug Discovery
Klara Livia Valko · IAPC Publishing eBooks · 2012
2.2. THEORETICAL BACKGROUND OF HPLC 65 2.2.1. Direct measurement of lipophilicity by chromatographic methods 68 2.2.2. Measurements of lipophilicity using isocratic chromatographic retention ......70 2.2.3. Measurements of lipophilicity using gradient chromatographic retention ......73 2.2.4. pH dependence of lipophilicity and reversed phase chromatographic retention 74