AlkD has six HEAT-like tandem repeats
Bjørn Dalhus, Helle, Ina Høydal, Backe, Paul H., Ingrun Alseth, Torbjørn Rognes, Magnar Bjørås, Laerdahl, Jon K. · Figshare · 2011
Copyright information:Taken from "Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats"Nucleic Acids Research 2007;35(7):2451-2459.Published online 29 Mar 2007PMCID:PMC1874660.© 2007 The Author(s) Structure-based multiple alignment of repeats R1 (α1 and α3), R2 (α4 and α5), R3 (α6 and α7), R4 (α8 and α9), R5 (α10 and α11) and R6 (α12 and α13) of AlkD with conserved residues shown on a coloured background; hydrophobic residues blue, basic residues orange, acidic residues magenta and polar Tyr and Gln residues light blue and green, respectively. Each α-helix (H_in) of the putative DNA binding surface of AlkD is linked to the two rear side α-helices (H_out), the one preceding it (same repeat) and the other succeeding it (next repeat), through short loops. There is an additional inserted α-helix, α2 (boxed, magenta), between the first and second α-helices of R1.