First extracted sub-graph
Rainer König, Gunnar Schramm, Marcus Oswald, Hanna Seitz, Sager Sebastian, Zapatka Marc, Gerhard Reinelt, Eils Roland · Figshare · 2011
Copyright information:Taken from "Discovering functional gene expression patterns in the metabolic network of with wavelets transforms"BMC Bioinformatics 2006;7():119-119.Published online 8 Mar 2006PMCID:PMC1434775.Copyright © 2006 König et al; licensee BioMed Central Ltd. Green boxes indicate significant up-regulation (p-value ≤ 0.05) under anaerobic conditions. Red boxes indicate significant down-regulation and grey boxes non-significant differential regulation. Red/green frames of grey boxes indicate a non-significant tendency. Glucose is catabolised into pyruvate. Under anaerobic conditions, pyruvate is degraded to formic acid (formate), which is either expelled (via transporters), or further degraded into Hand CO. The reactions for these processes were up-regulated whereas the biosynthesis and degradation of costly compounds were down-regulated (folate and 10-formyl-THF, respectively).