Modeling of Continuity and Change in Biology.
Vinay K. Chaudhri, Frank Loebe · 2014
Abstract. Continuity and change is a core theme in biology that refers to how genetic information is carried forward. This paper reports on our initial steps to-ward representing this core theme and describes the methodological background and open challenges. We define continuity and change from a conceptual mod-eling perspective, identify its facets that require further ontological work, and present competency questions designed to check the adequacy of its represen-tation. Moreover, we explore whether continuity and change must be explicitly represented as primitives in the representation of biological processes or whether it can be inferred from the process structure.