Inhibitory Effect of Protein of Eupolyphaga sinensis Walker and Medicated Serum on HepG-2 and MCF-7 Cell Line
Yun Ye · Lishizhen Medicine and Materia Medica Research · 2011
Objective To investigate the inhibitory effect of protein of Eupolyphaga and medicated serum on HepG-2 and MCF-7 cell line.Methods Protein of Eupolyphaga was prepared.After taking protein of Eupolyphaga,mouse serum was prepared.Both of them were added into HepG-2 and MCF-7 cell line respectively to examine the inhibitory activity proliferation by the MTT assay.Results To the HepG-2 cell,protein of Eupolyphaga had no anti-proliferation activity,while medicated on serum had obvious anti-proliferation activity.To the MCF-7 cell,both protein of Eupolyphaga and medicated serum could inhibit cell multiplication,and its medicated serum was the most remarkable.Conclusion The serum pharmacology can reflect pharmacological action actually.The protein of Eupolyphaga has an obvious inhibitory effect on the proliferation of HepG-2 and MCF-7 cell.