Research progress in adverse drug reaction signal detection methods based on spontaneous reporting system
LI Yuan-y · Anhui Medical and Pharmaceutical Journal · 2015
Adverse drug reaction( ADR) monitoring work is one of the important components of post- marketing safety evaluation. In foreign countries studies had been carried out early on the adverse reactions of signal detection method based on spontaneous reporting system( SRS),but the specific ones vary. Now,there is no gold standard. This article analyzes the classical and drug combinational adverse drug reaction signal detection methods at home and abroad and their use condition,and discusses the advantages and disadvantages of each one. Signal detection system for adverse drug reactions( ADR) adaptable to China was proposed to provide some references for adverse drug reaction signal detection work.