Discussion on application of review criteria by Sysmex XE-2100 automatic hematology analyzer
Fan Zhang · Journal of Huaihai Medicine · 2013
Objective To assess the validation of 23 review criteria recommend by experts using Sysmex XE-2100 automatic hematology analyzer so as to develop a set of suitable re-examination rules for hospital patients.Methods 1229 blood samples having being examined by instrument were selected.Their pushing slides,blood smears and staining were prepared for microscopic examination.The outcomes were compared with the 23 review criteria recommended by experts.Appropriate modifications of the criteria were then made based on false positive and negative results.Results 700 samples were tested using the 23 review criteria recommended by the experts,of which 23.% were the true positive,13.28% the false positive rate,61.% the true negative,and 2.71% the false negative.The rate of pushing slice was 36.28%.In contrast,529 specimens were tested using the modified 20 rules.The result showed a true positive rate of 24.76%,a false positive rate of 3.59%,69.37% for the true negative and 2.27% for the false negative.The rate of pushing slice was 28.35%.Conclusion The suitable modified 20 re-examination rules for blood counting and smear based on the characteristics of the instrument and the regional practical situation can ensure the quality of the test and improve work efficiency.