The impact of initiation timing of dialysis on the outcome in peritoneal dialysis patients
Chen Zi-ju · Journal of Tropical Medicine · 2015
Objective To study the effect of initiation timing of dialysis on clinical outcome in peritoneal dialysis patients and its risk factors. Methods According to the inclusion and exclusion criteria,patients have been recruited in the peritoneal dialysis center of our hospital from January 1,2010 to December 31,2012. The patients were divided into three groups according to the eGFR at the start of dialysis: group A,eGFR5 ml /(min·1.73 m2),group B,eGFR 5~10 ml /(min·1.73 m2),group C,eGFR10 ml /(min·1.73 m2). The survival rates of three groups were compared using the Kaplan-meier analysis,and risk factors for death in dialysis patients were analyzed by COX regression. Results Overall 286 patients were recruited into this study. The survival rate of group A was significantly lower than that of group B,and there was no significant difference between group B and group C. Starting very late to dialysis,older,diabetes mellitus and hypoalbuminemia were the independent risk factors of mortality in peritoneal dialysis patients. Conclusion Too late to dialysis may be a risk factor for death in patients with peritoneal dialysis,but too early to dialysis does not improve the prognosis of patients. In addition,older,diabetes mellitus and hypoalbuminemia were the independent risk factors of mortality in peritoneal dialysis patients.