Advances in single biomolecule research
Kechun Lin · Acta Biophysica Sinica · 2001
Most molecular biological experiments represent measurements of ensemble average by which a vast multitude of duplicate systems are probed and average responses are recorded. With advances in techniques we are able to observe, detect,manipulate individual molecules and study their conformational change and dynamic behaviors. New information could be seen from these single molecules research which were otherwise be hidden or averaged out. Advances in this field is a new direction of structural biology for this century.