Effect of DMT 1 on Gene Expression in the Process That THP-1 in Oxidizing LDL
Junzhu Wu · Journal of Wuhan Bioengineering Institute · 2007
RT-PCR and Western blot were adopted to verify the action performed by divalent metal transporter 1 (DMT 1) in the process of oxidation mediate human THP-1 monocyte and low density Iipopro-tein (LDL). Result showed that DMT 1 was involved in the process of the above-mentioned oxidation, in which the mRNA express level rose significantly. The result also suggested a new train of thought for clinical anti-oxidized treatment upon cardiovascular disease.