Test of some indexes about pre-thrombotic state in the patients with severe pneumonia
XU Guo-fen · Laboratory Medicine and Clinic · 2009
Objective To observe part of the indexes about pre-thrombotic state(PTS) in patients with severe pneumonia,and to explore the clinical meaning.Methods To analyse the index of PT,APTT,Fg,D-Dimer and FDP,and count the number of both the planet(PLT) and white blood cells(WBC) of 88 patients with severe pneumonia and 80 healthy persons retrospectively.Results Compared with the control group,the number of PLT of the group with severe disease decreases while WBC increases,PT and APTT prolongs,and the value of Fg is raised,D-D and FDP become positive in the group with severe pneumonia(P0.05).Level of PLT is related to PT,APTT and Fg(r=0.416,0.521,0.458),and so is WBC(r=0.387,0.524,0.486).Conclusion The mechanism of coagulation and fibrinolytic function becomes disorder for the patients with severe pneumonia.It may be related to the inflammation.Important attention should be paid-ed to the index,which might be helpful for the diagnosis and treatment of severe pneumonia.