Effect of antibactrial proteins of Musca domestica Larvae on A_(375)
Wan Qi-hui · Chinese Journal of Public Health · 2006
Objective To explore the inhibitory effects of the antibactrial proteins from the Musca domestica larvae on the A_(375).Methods The effects of the antibactrial proteins from the Musca domestica larvae for the growth of the A_(375) were observed by cytometry,MTT assay and acridium orange stainings.The effects of the antibactrial proteins from the Musca domestica larvae for the growth of the periodontal membrane cell of human were observed by MTT assay.Results At the high-concentration groups,the cell number and the optical density(OD) of A_(375)were significantly decreased,the apoptosis index(AI) was measured.With the increase of the concentration,the inhibitory rate of the cell proliferation wer increased.The OD and the inhibitory rate of the cell proliferation at the all concentration-groups had hardly difference compared with the control group in the periodontal membrane cell of human.Conclusion The antibactrial proteins from the Musca domestica larvae might be inhibited the growth of A_(375)by inducing cell apoptosis.The antibactrial proteins from the Musca domestica larvae could hardly inhibited the normal human cell.The inhibition effects had a threshold.