Hematology Analyzers Counting Platelet Pseudo-abnormality and Its Influencing Factors
Ying Jie Sun · Medical Recapitulate · 2013
Objective To investigate reasons of pseudo-abnormality of the blood analyzer in the platelet count and the countermeasures.Methods From November 2008 to November 2011,blood specimens of 544 patients from Beijing Tiantan Hospital were retrospectively analyzed,on the basis of platelet histogram and the MCV and MPV parameters,the screening were divided into group A of 270 cases(normal volume platelets),50 cases in group B(large platelets),62 cases in group C(platelet aggregation),90 cases in group D(red cells appearing interference),72 cases in group E(red cell fragments appearing interference);instrument method and manual method were applied for platelet counting results comparison.Results In group A,histogram showed normal distribution,test results of the instrument and microscopic counting had no statistically significant difference(P0.05);and group B,C,D,E of the abnormal distributed platelet histogram,the instrument test results were statistically significantly different from the microscopic counting results(P0.01).Conclusion The application of hematology analyzer for blood platelet detection has a lot of influencing factors,which needs not only the correct operation,but also exclusion of the interference of various factors,and necessary measures should be taken for recheck,to ensure the accurate and reliable test results.