Quantitative Structure-pharmacokinetic Relationship in Drug Design and Discovery
Xijing Chen · Yaoxue jinzhan · 2009
The definition and approach of research on quantitative structure-pharmacokinetic relationship (QSPR) were outlined.The prediction of pharmacokinetics,including prediction of drug absorption,distribution,metabolism and excretion (ADME),by QSPR models and the guiding significance of QSPR in drug design and discovery were reviewed.