Amlodipine and Atorvastatin Calcium Tablets on Hypertension Complicated with Coronary Heart Disease Clinical Analysis
Leilei Wang · Xiandai shengwu yixue jinzhan · 2013
Objective: To investigate the clinical curative effect of amlodipine and atorvastatin in treating hypertensive patients with coronary artery disease.Methods: 58 patients diagnosed with essential hypertension and coronary heart disease in our hospital during June 2008 and December 2011 were randomly divided into observation group and control group,under the premise of informed consent,with 29 cases in each group.The control group were treated by atorvastatin,and the observation group were treated by amlodipine and atorvastatin.After treatment compared the blood pressure,electrocardiogram,adverse reactions and other indicators,and analyzed the therapeutic effect and safety.Results: After treatment,the improving efficiency of blood pressure and ECG in control group was respec-tively 72.4% and 55.2%,and that of the observation group was respectively 96.6% and 93.1%.The observation group improved greater than the control group.The complication rate was 10.3% for both groups,with no statistically significant difference.Conclusion: Am-lodipine and atorvastatin had obvious curative effect in treatment of essential hypertension with complication of coronary heart disease,with advantages like high safety and low cost,so it is worthy of clinical application.