Study on the Mechanism of Visual Coding and Language Activities of Children with Chinese Dyslexia by fNIRI
Han Wu · Chinese Journal of School Health · 2004
Objective To explore the functions of the prefrontal cortex and the changes of cerebral blood oxygenation of children with Chinese dyslexia in visual coding. Methods Nineteen children with Chinese dyslexia were taken as cases matched with 28 uormal children. Their ages were(9.81±1.22)and(9.77±1.19)respectively. When the subjects were accomplishing the tasks of single word component processing and visual coding, functional near infrared imagining (fNIRI)were used to detect the diffusion intensity of 760 nm and 850 nm near infrared penetated through the frontal bone and the left prefrontal cortex and the changes of the cerebral blood volume and blood oxygenation. Results The changes of BOLD were stronger during accomplishing single word component than visual coding processing in dyslexia and control children. During visual coding processing left prefrontal CBV of RD children increased while the control group was on the contrary. And during single word component processing, rCBV increased in both groups, however the intensity and the area of regional cerebral activated were lower in RD children than in normal( P 0.05). Conclusion Left prefrontal lobe takes part in visual coding and single word component processing task. There are significant differences in rCBV metabolic mechanism and cerebral functional mechanism between RD children and normal children. Maybe nerve irregularity is the substance base for reading disorder.