Preparation Advances in Animal Models of Atherosclerosis
LI Mei-fan · Medical Recapitulate · 2013
As a chronic inflammatory disease,not only atherosclerosis is a common pathophysiological process of most cardiovascular diseases,but also its complications are the major reasons contributing to patients' lethality and disability.The pathogenic mechanisms of atherosclerosis are not completely elucidated,thus preparation of animal models of atherosclerosis plays an extremely important role in studying its pathogenesis,pathological changes,as well as prevention and treatment.Although a variety of animal models have been used to research atherosclerosis formation,an ideal animal model has not been found,which can exactly simulate human atherosclerosis disease processes.