Study on real-time medical image registration based on mutual information

Guo Qing-yu · Computer Engineering and Applications Journal · 2011

The medical image registration based on mutual information is a high-precision registration method,which can reach sub-pixel accuracy with no need to extract anatomical features from images.But it can not meet the need of real-time clinic due to its low speed.This paper proposes a speed program:a rough registration to narrow the range of mutual information search,a method of gray-scale compression based on a gray histogram for speeding up mutual information computation, a hybrid optimization algorithm of genetic algorithm and simplex method for convergence acceleration.Experiments show that the modified method can significantly reduce the registration time.

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