Diagnostic Value of the Changing of Kidney Blood Flow Detected by Color Doppler Ultrasonography in Preclinical HRS
Hao Dian-ji · Zhongguo quanke yixue · 2010
Objective To study the application value of color Doppler ultrasonography in the diagnosis of preclinical hepatorenal syndrome.Methods The resistance index of the interlobar arteria hemodynamics as well as urinary α1-MG of the patients with compensatory(30 cases) and uncompensatory(30 cases) liver cirrhosis were examined with color Doppler ultrasonography,and the renal function of these patients was normal.The healthy volunteers were selected as the control group.Results The resistance index(RI) of the compensatory group and control group were(0.59±0.06) and(0.57±0.08) respectively,there were no statistical differences between the two groups(P0.05).The RI of the uncompensatory group were(0.62±0.04),there were statistical differences between this group and the compensatory as well as control group(P0.05).The level of urinary α1-MG of the control group was(5.61±0.35)mg/L,and the level of urinary α1-MG of the compensatory group and the uncompensatory group was(8.15±2.87)mg/L and(28.07±20.58)mg/L respectively,and there were statistical differences between the uncompensatory group and the other two groups in the level of urinary α1-MG(P0.05).If the value higher than 10.0 mg/L was chosen as the diagnostic criteria of preclinical hepatorenal syndrome,73.7% of the patients in the uncompensatory group could be diagnosed with preclinical hepatorenal syndrome,with RI all higher than 0.6.66.7% of the patients with RI0.6 could be diagnosed with preclinical hepatorenal syndrome.There were significant positive correlation between RI and α1-MG(r=0.499,P=0.049).Conclusion The renal hemodynamic changes become more and more severe in the progress of preclinical hepatorenal syndrome.There are many patients with preclinical hepatorenal syndrome in the uncompensatory group.Color Doppler ultrasonography can sensitively and objectively reflect the renal hemodynamic changes,for which it is important for the diagnosis of preclinical hepatorenal syndrome.