Advances in Insulintropic Peptides and GLP-1 Analogs
Yang Li-ping · Life Science Research · 2006
Recently,large amounts of insulintropic peptides and GLP-1 analogs with similar or relating structures and functions have been found from various kinds of natural lives,ranging from simple bacterials and epiphytes to evolutional reptiles and mammalias.Right now,the GLP-1 and some GLP-1 analogs have been focused and researched by gene engineering expression and chemistry synthesizing modification to develop new peptidal drugs to treat type 2diabetes.However,other insulintropic peptides,especially those being found from the secretions of amphibian skins and the venoms of rattle snakes,have not been attached enough attention.Obviously,those insulintropic peptides will certainly provide novel ideas and broad prospects to explore new drugs,with security,high efficiency,and long half-life to treat type 2 diabetes.