Progress of research on resistant mechanism of quinoline
Wang Jing · Junshi Yixue Kexueyuan yuankan · 2009
Resistance has become a big obstacle to the cure of malaria. As the leading medicament, quinolines used to be widely used but now the invalidation is deteriorating. In this article, the research progress in the relationship of resistance-related genes pfcrt, pfmdr1 and cg2 to the resistant mechanism of quinolines is reviewed.