Image registration based on improved gradient vector flow and maximization of mutual information

Xiuyou Wang, Jiwen Wang · Jisuanji gongcheng yu sheji · 2007

Multimodality medical image registration based on maximization of mutual information has been popular in medical image processing fields. Mutual information(MI)is successfully used as a similarity measure for both mono-and multimodality image regi- stration. However, MI measurement only takes statistical intensity information into account, and ignores spatial information in the images. A novel approach to incorporate spatial information into MI through gradient vector flow(GVF)is proposed. Multimodality brain image registration is performed to test the accuracy and robustness of the proposed method.

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