Selection of protein structure classification characteristics based on rough set
AO Pe · Jisuanji yingyong yanjiu · 2014
Scientific and reasonable classification attribute is critical for proper protein structure classification.This paper presented a method of selecting protein structure classification attributes based on rough set theory.Attribute values were obtained by multiple structure alignment tool MAMMOTH-mult.It proposed methods of simplified discernibility matrix and improved attribute reduction according to characteristic of elements in discernibility matrix.Data set of 35 families with complete information was taken as the research object in SCOP 1.71 database.The proposed method obtained % STRCTCORE and % LOOSECORE protein classification attributes.From scatter diagrams of structure alignment between d1a0fa1 and 35 families,46 626 family and 35 structures,it shows that the two protein classification attributes are taken as the standard of protein structure classification,protein structure can be classified correctly.