Advances in studies on anti-HIV alkaloids from natural product
Liu Guang-ming · Xiandai yaowu yu linchuang · 2012
In recent years, looking for efficiency and low toxicity of the lead compound from natural products has become the screening of anti-HIV drugs is an important research direction. Natural alkaloids as an important class of natural products has a large number and a complex structure type, which has a variety of suppression and blocking of the active ingredients of HIV infection, it is expected to derive an effective anti-HIV drugs by way of laboratory research work and clinical use. This article is based on the chemical structure of alkaloids, which be divided into 10 classes, such as isoquinoline alkaloid, quinoline alkaloids, macrocyclic alkaloids, piperidine alkaloids, tropane alkaloids, indole alkaloids, carbazole alkaloid, marine polycyclic guanidine alkaloids, terpene alkaloids, manzamine-type alkaloids, briefly reviewed anti-HIV activity of alkaloids compounds.