ANN Based Application of Pharmacogenetics to Personalized Cancer Treatment
Bekir Karlık, Emre Öztoprak · 2012
Artificial Neural Networks (ANN) may probably be the single most successful technology in the last two decades which has been widely used in a large variety of applications in biomedical areas. ANN is used in pharmaceutical (pharmacokinetic and pharmacogenetic) areas to model complex interactions and predict the nonlinear relationship between causal factors and response variables. The aim of this study is indicate a novel approach on application of pharmacogenetics to personalized cancer treatment using data of TPMT polymorphisms and ANN.