Pharmacophore-based Virtual Screening in Drug Discovery
Christian Laggner, Gerhard Wolber, Johannes Kirchmair, Daniela Schuster, Thierry Langer · Royal Society of Chemistry eBooks · 2008
In past years, considerable efforts have been devoted to compacting the early phase of hit-to-lead development in the drug discovery process within the pharmaceutical industry. In particular, as combinatorial chemistry and high-throughput screening failed to show the expected success, in silico-base...