The Estenfication of Gibberellins with Dimethylformamide Dimethyl Acetal (DMFDMA)
Muhammad Shaiq Ali, James R. Hanson, Viqar Uddin Ahmad · Zeitschrift für Naturforschung B · 1997
The key step is to prepare rare gibberellins by converting the more readily available gibberellins (GA3, GA4, GA7 and GA13) into their m ethyl esters. The DMFDMA is employed as an esterifying reagent to avoid the diazom ethane due to its toxic, explosive and hazardous nature. It is observed that DMFDMA apart from esterification can also be used as acetylating and epimerizing reagent.