Identification, characterisation and exploitation of novel Gram-negative drug targets

Gunter Schneider, Tatyana Sandalova, J. Kopec, Jason W. Schmidberger, R. Schnell · Acta Crystallographica Section A Foundations of Crystallography · 2010

Page s34 s34forms a polyproline-II-like helix that seems to be a common feature of many Gram-positive cell-wall anchored virulence factors, and particularly of basal pilins.Together, we identified structural characteristics of pilins that direct their incorporation into the pilus polymer.

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