QSAR Modeling of Carbonic Anhydrase-I, -II and -IV Inhibitory Activities: Relative Correlation Potential of Six Topological Indices
Padmakar V. Khadikar, Brian W. Clare, Alexandrù T. Balaban, Claudiu Trandafir Supuran, Vijay K. Agarwal, Jyoti Singh, Ashok Joshi, Meenakshi Lakhwani · UWA Profiles and Research Repository (University of Western Australia) · 2006
QSAR studies on modeling the biological activities of 26 benzenesulfonamide derivatives as inhibitors of carbonic anhydrases CA-I, CA-II and CA-IV were performed using six distance-based topological indices, including Balaban-type indices J(hetV) and J(hetE). Satisfactory multiparametric correlations were obtained.