The history, evolution and importance of lipophilicity in medicinal chemistry: from Hippocrates and Galeno to Paracelsus and the contributions of Overton and Hansch

Luciano José Nogueira, Carlos Alberto Montanari, Cláudio Luis Donnici · Revista Virtual de Química · 2009

introduction about the history of Medicinal Chemistry and the importance of lipophilicity in this development; among others the contributions of Hippocrates, Galeno, Paracelsus, Overton, Ehrlich and Hansch are remarkably noticed.

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