Toxicogenomics in drug development: a match made in heaven?
Chunhua Qin, Keith Quincy Tanis, Alexei A. Podtelezhnikov, Warren E. Glaab, Frank D. Sistare, Joseph J. DeGeorge · Expert Opinion on Drug Metabolism & Toxicology · 2016
Compound toxicity accounts for approximately half of all drug failures during development. Currently accepted preclinical studies for drug safety evaluation are time, resource, and animal intensive...