Copper Triflate: An Efficient Catalyst for Direct Conversion of Secondary Alcohols into Azides
Anil Kumar, Poonam Khedar, Kasiviswanadharaju Pericherla · Synlett · 2014
A simple, practical, and efficient strategy has been demonstrated for the direct synthesis of organic azides from alcohols using azidotrimethylsilane (TMSN 3 ) as azide source in the presence of copper(II) triflate [Cu(OTf) 2 ]. A variety of alcohols was converted into the corresponding azides in good to excellent yields. The formation of an intermediate carbocation was confirmed by the synthesis of bis(diphenylmethyl) ether.