To Freeze or Not to Freeze:A Comparison of Methods for the Handling of Breast Biopsies With No Palpable Abnormality
Theodore H. Niemann, Joel G. Lucas, William L. Marsh Jr. · American Journal of Clinical Pathology · 1996
Recently there have been several editorials suggesting that breast biopsies with small or nonpalpable lesions should not be subjected to frozen section examination. In this study, the approach of routinely performing frozen sections on all breast biopsies was compared to the recommended approach of performing frozen sections only on cases with gross lesions 1.0 cm and were subjected to frozen section examination. The remaining 291 cases contained either no distinct lesion or a gross lesion 1.0 cm improves frozen section accuracy. This study provides statistical support for previous recommendations that frozen section examination should be limited to cases with distinct gross lesions > 1.0 cm.