Large Scale Modelling Of Two-dimensional Cardiac Tissue Using Parallel Methods
Nicos Maglaveras, K. Margaritis, J. de Bakker, Frans J.L. van Capelle, M. AHessie, M.G. Strintzis, C. Pappas · WIT transactions on biomedicine and health · 1970
Finite difference and iterative methods are used to simulate two-dimensional impulse propagation in cardiac tissue. The model used takes explicitly into account the effects of cytoplasmic and junctional resistances. An initial parallel approach for the implementation of the iterative methods (Gauss-Seidel in our case) based on the systolic array method is presented. The number of iterations needed for convergence of the iterative methods at each time step is examined in conjunction with changes in the spatial distribution of the electrophysiologic parameters such as coupling resistance. Electrograms and propagating action potentials (PAP) are calculated for cases simulating infarcted hearts by placing dead cell bariers in the model cardiac tissue sheet. The shapes of the electrograms and PAPs are critically depending on the position of the recording site relative to the dead cell barriers.