Expert diagnostic system for hemoglobinopathies using the data on blood, erythrocyte, and hemoglobin state
Elvira Ilgizovna Nasybullina, Валентин Григорьевич Никитаев, А. Н. Проничев, Valentina Nikolaevna Blindar, Olga Vladimirovna Kosmachevskaya, Alexey Fedorovich Topunov · Bulletin of the Lebedev Physics Institute · 2015
A conceptual model of the expert system (ES) of hemoglobinopathy diagnostics is considered. The ES core is the knowledge base (KB) including grouped data on qualitative and quantitative blood indicators, among which is the amount of membrane-bound hemoglobin, i.e., a new indicator in hematological practice. Quantitative indications are complemented by qualitative ones reflecting morphological changes of pathological erythrocytes. The presented ES is a tool for supporting doctor decision making in hemoglobinopathy diagnostics.