Compression and fast retrieval of genomic wide genetic variants
Denis Altomare · 2015
This thesis presents several improvements to SNPack 1.0, a state of the art algorithm for compressing and retrieving genetic data, designed for large scale association studies. The algorithm has been improved in terms of compression time, compression ratio, loading time and type of data that can be handled. A comparison with SNPack 1.0 and with the other state of the art tools highlights the superior performance of the new SNPack version