Grammar-based Compression of DNA Sequences

Neva Cherniavsky, Richard E. Ladner · 2007

Grammar-based compression algorithms infer context-free grammars to represent the input data. The grammar is then transformed into a symbol stream and finally encoded in binary. We explore the utility of grammar-based compression of DNA sequences. We strive to optimize the three stages of grammar-based compression to work optimally for DNA. DNA is notoriously hard to compress, and ultimately, our algorithm fails to achieve better compression than the best competitor. 1

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