Development of decision support systems for sampling germplasm
Jean-Pierre Jacquemoud-Collet, Xavier Perrier, Claire Billot, Brigitte Courtois, Monique Deu, Samy Gaiji, Rajesh Sood, M.C.A.M. Bink · Agritrop (Cirad) · 2005
Rationale and Objective address the needs formulated by SP1 scientists -localize genes involved in agronomic traits, in using molecular markers as tags -detection by association mapping based on disequilibrium between linked loci on germplasm collections to track a large allelic diversity but… composite collections = complex pools of genetically differentiated objects: wild ancestors, relatives, landraces, inbred lines, elite material … accumulating various demographic/breeding events: selection, genetic drift, bottleneck, founder effects … → Structured populations with disturbed balances of alleles generating spurious associations and disequilibria even between unlinked loci 3 Rationale and Objective Practical constraint: phenotyping is long and expensive and can concern only a small part of the collectionCombining the two problems :how to take advantage of the necessary sampling to minimize disequilibria due to structures? Generation Challenge Programme