The ELF Honest Data Broker: informatics enabling public–private collaboration in a precompetitive arena
G. Paillard, Philip J. Cochrane, Philip S. Jones, Willem P. van Hoorn, Andrei Caracoti, Herman van Vlijmen, Andrew Pannifer · Drug Discovery Today · 2015
New precompetitive ways of working in the pharmaceutical industry are driving the development of new informatics systems to enable their execution and management. The European Lead Factory (ELF) is a precompetitive, 30-partner collaboration between academic groups, small-medium enterprises and pharmaceutical companies created to discover small molecule hits against novel biological targets. A unique HTS screening and triage workflow has been developed to balance the intellectual property and scientific requirements of all the partners. Here, we describe the ELF Honest Data Broker, a cloud-based informatics system providing the scientific triage tools, fine-grained permissions and management tools required to implement the workflow.