Using Hidden Markov Models to capture temporal aspects of ultrasound data in prostate cancer
Layan Nahlawi, Farhad Imani, Mena Gaed, José A. Gómez, Madeleine Moussa, Eli Gibson, Aaron Fenster, Aaron D. Ward, Purang Abolmaesumi, Parvin Mousavi, Hagit Shatkay · 2015
Recent studies highlight temporal ultrasound data as highly promising in differentiating between malignant and benign tissues in prostate cancer patients. Since Hidden Markov Models can be used for capturing order and patterns in time varying signals, we employ them to model temporal aspects of ultrasound data that are typically not incorporated in existing models. By comparing order-preserving and order-altering models, we demonstrate that the order encoded in the series is necessary to model the variability in ultrasound data of prostate tissues. In future studies, we will investigate the influence of order on the differentiation between malignant and benign tissues.