Structure Activity Relationships (SARs) Using a Structurally Diverse Drug Database: Validating Success of Predictor Tools.
Malcolm J. D’Souza, Fumie Koyoshi, Lynn M. Everett · PubMed · 2009
predictors. 14 pertinent pharmaceutical and pharmacological properties were collected for 75 structurally diverse consumer prescription drugs, and for several drugs, not all properties were completely populated. The major objective of this investigation was to validate the platforms prediction models for plasma protein binding (PPB) and bioavailability (BIO).