N-Bromoisonicotinamide: new, mild, stable, effective and efficient oxidant for organic substrate.
M. Balasubramaniyan, N. Mathiyalagan · Oriental Journal Of Chemistry · 2010
N-Bromoisonicotinamide (NBIN) is prepared by standard procedure and characterized. The physical constant, the formal redox potential, elemental analysis and spectral characterization (IR and 1H NMR) confirm the presence of nitrogen-halogen bond. It is found to be a stable and mild oxidant of low cost. It is prepared by a simple method, giving high yield in a short period of time. Its formal redox potential shows NBIN can be used as effective source of positive halogen. It will be a valuable addition to the existing oxidants. It is screened for antimicrobial activity against bacteria and fungi at various concentrations using disc diffusion method.