Strategic Data Handling for Pharmacometrics
Timothy T. Bergsma · 2011
with potentially powerful eect. Many pharmacometric data handling operations may be expressed succinctly using the functions described, all of which respect original record order. In fact, record order is central to the computational strategy of nth (etc.). In contrast, record order is computationally immaterial for reapply when used with a scalar function argument, such as mean, but will be consequential when reapply is used with\longitudinalisometric vector processors, e.g., cumsum and rev (but not sort). In summary, stableMerge, nth (etc.), and reapply promote strategic data handling for pharmacometrics by enabling succinct, expressive, rapid data assembly techniques that respect record order.