Proteins Structure Determination with Imprecise Distances
Ivan da Silva Sendin, Siome Klein Goldenstein · 2013
The Molecular Distance Geometry Problem is related to protein structure determination using Nu- clear Magnetic Resonance information which is imprecise distances of some proteins atoms. Most current methods available to solve this problem work with exact distances. We propose three new methods to propagate uncertainty: using particles, using affine forms and hybrid affine-particles. We use these new methods to propagate uncertainty and determine the protein backbone using NMR like information.