Comparison of Topology-preserving Segmentation Methods and Application to Mitotic Cell Tracking
Martin Burger, Hendrik Dirks, Joana Sarah Grah, Jonas Geiping · 2014
This thesis compares two representative methods that constrain the topology of an active contours segmentation, the digital Simple-Points scheme and the variational Repelling-Snakes topology preservation. The comparison will be facilitated at the example of the MitosisAnalyser framework, a tool designed to find mitotic cells in phase contrast microcopy videos. It turns out that Repelling-Snakes is better suited for topology preservation for this framework than the Simple-Points scheme that was used before. Stable and efficient numerical implementations will also be presented.