10.51847/GXlTrkJ
Prafulla Balkrishna Choudhari, Manish Sudesh Bhatia · Time to knit · 2000
Factor IXA now a day is becoming attractive target for many researchers for the designing novel anticoagulants. The advances in the computational chemistry can be use full for designing of new chemical entities. The pharmacophore identification and QSAR studies on reported 51 factor IXa inhibitors have been carried out. QSAR model developed considering training and test set approaches with stepwize variable selection method. QSAR models which were further validated for statistical significance a