Steric acceleration of intramolecular azide cycloadditions
Barry S. Orlek, Peter G. Sammes, David J. Weller · Journal of the Chemical Society Chemical Communications · 1993
Use of conformational restraints, induced by different ortho-substituents in 1-allyloxy- and 1-prop-2-ynyloxy-2-azidomethylbenzenes, can be employed to enhance the smooth intramolecular addition of the azide group to the unsaturated bond, followed by, in one example, removal of the conformational constraint.