An Efficient Implementation of a Drug Candidate Database
Zina Ben Miled, Yang Liu, David M W Powers, Omran Bukhres, Michael Bem, Robert Jones, Robert J. Oppelt · Journal of Chemical Information and Computer Sciences · 2002
The recent advances in laboratory technologies have resulted in a wealth of chemical and biological data. The rapid proliferation of a vast amount of data has led to a set of cheminformatics and bioinformatics applications that manipulate dynamic, heterogeneous, and massive data. An example of such application in the pharmaceutical industry is the computational process involved in the early discovery of lead drug candidates for a given target disease. In this paper, an efficient implementation of a drug candidate database is presented and evaluated. This study shows that high performance data access can be achieved through proper choices of data representation, database schema design, and parallel processing techniques.