Quantitative structure-activity relationships for predicting skin and eye irritation
Grace Y. Patlewicz, Rosemary Rodford, John David Walker · Environmental Toxicology and Chemistry · 2003
Recent quantitative structure-activity relationships (QSARs) for the prediction of skin and eye irritation were reviewed. The QSARs in these areas are hindered by the lack of quality in vivo data and by a lack of understanding of the mechanisms of action. Creation of appropriate data sets for experimentation would facilitate the development of robust QSARs for predicting skin and eye irritation.