Laplace-filter enhanced haptic rendering of macromolecule s
O. Passon, Maik Boltes, Stefan Birmanns, H. Zilken, Willy R. Wriggers, Angewandte Mathematik · JuSER (Forschungszentrum Jülich) · 2005
The modeling of large biomolecular assemblies fre-quently requires a combination of multi-resolution data from a variety of biophysical sources. Sev-eral algorithmic solutions to this docking problem have been proposed which are usually based on the spatial cross correlation. In [1] it was shown that Laplace-filtering techniques can improve the docking performance of these algorithms. This note presents the implementation and first results of the Laplace-filter enhanced fitting into the interac-tive SenSitus program, which supports the docking by virtual reality (VR) techniques (3D-stereoscopic view and haptic rendering). This implementation has to consider the special needs of the interactive rendering strategy. We employ reduced models us-ing vector quantization to achieve the required force update rate. 1